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gradually deepening understanding of Tumor stem cells of the tumor along with the deepening mechanism was put forward a new concept, it is both normal stem cells in close contact, there are significant differences.

Medical research shows that cancer stem cells and normal stem cells is the difference between the source and nature of its decisions. Cancer stem cells derived from tumor tissue, while the normal stem cells from normal tissue. Specifically, the first self-renewal of normal stem cells have a mechanism for feedback regulation, proliferation and differentiation in equilibrium, is orderly; in cancer stem cells [link widoczny dla zalogowanych], this regulatory mechanism has been unbalanced, it is a disorderly proliferation and differentiation, and out of control of. Second, cancer stem cells without the ability to differentiate into mature cells, their abnormal differentiation program, which is a normal differentiation program of stem cells are essentially different. Finally, the cancer stem cells tend to accumulate replication errors, and normal stem cell development mechanism to prevent this phenomenon. Therefore, the concept of cancer stem cells suggested that more is embodied in the knowledge of the mechanisms of
19 centuries since the 80's, researchers discovered that stem cells and cancer cells share a surprising similar. Teratocarcinoma as malignant and normal fetal tissue with similar high-copy [link widoczny dla zalogowanych], poorly differentiated features, similar to the signaling pathway may regulate both stem cells, cancer cells also regulate self-renewal. Medical experts had speculated in the 20th century, there is a certain cancer cells can keep the mother cell self-renewal, that "cancer stem cells." This speculation is based on the theory, whether it is cancer or normal tissue cells by heterogeneous group composed of these cell groups have their own phenotypic characteristics and proliferative potential. The growing body of evidence also shows that: cancer stem cells is a stem cell characteristics, as gene mutations (including the abnormal chromosome number and structure of the exception) or molecular abnormalities (including the cancer genes, cancer genes, drug-related molecular abnormalities ) resulting from abnormal cellular function of a class of malignant cells.
Recently published "Cancer Cell" to a new study published in the journal the results show that the United States researchers first successfully cultured from normal tissue of breast cancer stem cells. Experts said the research is expected to further deepen the scientific community on the mechanism of cancer research and awareness, and to find radical new ways of cancer.
valuable research Chinese Academy of Medical Sciences, Institute of Basic Medical Cell Head Professor Zhao Chunhua [link widoczny dla zalogowanych], said U.S. researchers published the results is a valuable research. First of all, they are the first from the normal breast tissue cells isolated from two different subsets, and confirmed that they can be converted to the corresponding in vitro characteristics of two different breast cancer cells (HMECs and BPECs), and these two cells form tumors xenografts in the group of features, tumorigenicity, and invasive with significant differences on. In addition, the researchers first used the new training system for breast cancer in normal breast cells to cell transformation provides a new research model, cancer research provides a new way of thinking.

cer cell proliferation and metastasis are characterized by a large class of diseases. 2000 new cancer cases worldwide of about 1,000 people, killed 620 people; expected new cases of cancer in 2020 will reach 1500 million people, killed 1,000 people. "Cancer Prevention and Control Program for 2004-2010" states: cancer is becoming the first killer of mankind in the 21st century.
Cancer research has been classified as "national long-term Science and Technology Development Plan" in the need to focus on resolving one of the major diseases.

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